The white light video on the left shows the phantom and the axial retraction of the device. The beam can be seen sweeping along the lumen surface and the video on the right is being generated in real-time. The signals from all the SERS flavors as well as the topography information are being acquired simultaneously and displayed in realtime. The data is initially displayed from an intraluminal view which is a similar view obtained from white the white light endoscope, but is easily rotated by the user.
Citation: Garai E, Sensarn S, Zavaleta CL, Loewke NO, Rogalla S, et al. (2015) A Real-Time Clinical Endoscopic System for Intraluminal, Multiplexed Imaging of Surface-Enhanced Raman Scattering Nanoparticles. PLoS ONE 10(4): e0123185. doi:10.1371/journal.pone.0123185
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Real-time, multiplexed imaging overlaid onto 3D lumen topography in a colon phantom. |
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